1. Publications
  1. do Rego J-C, Suaudeau C, Chapouthier G, Costentin J. Mouse lines differing in sensitivity to beta-CCM differ in tasks used for testing antidepressants. Pharmacol. Biochem. Behav. 72, 411-416 doi: 10.1016/s0091-3057(01)00761-4 (2002).
  2. Le Cudennec C, Naudin B, do Rego J-C, Costentin J. Nociceptin/Orphanin FQ and related peptides reduce the increase in plasma corticosterone elicited in mice by an intracerebroventricular injection. Life sci. 72, 163-171 doi: 10.1016/s0024-3205(02)02218-x (2002).
  3. Chartrel N, Dujardin C, Anouar Y, Leprince J, Decker A, Clerens S, do Rego J-C, Vandesande F, Llorens-Cortes C, Costentin J, Beauvillain JC, Vaudry H. Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity. Proc. Nat. Acad. Sci. USA 100, 15247-15252 doi: 10.1073/pnas.2434676100 (2003).
  4. Fichna J, do Rego J-C, Costentin J, Chung NN, Schiller PW, Kosson P, Janecka A. Opioid receptor binding and in vivo antinociceptive activity of position 3-substituted morphiceptin analogs. Biochem. Biophys. Res. Comm. 320, 531-536 doi: 10.1016/j.bbrc.2004.05.202 (2004).
  5. Fichna J, do Rego J-C, Kosson P, Costentin J, Janecka A. Characterization of antinociceptive activity of novel endomorphin-2 and morphiceptin analogs modified in third position. Biochem. Pharmacol. 69, 179-185 doi: 10.1016/j.bcp.2004.09.011 (2005).
  6. Kruszynski R, Fichna J, do Rego J-C, Chung NN, Schiller PW, Kosson P, Costentin J, Janecka A. Novel endomorphin-2 analogs with µ-opioid receptor antagonist activity. J. Pept. Res. 66, 125-131 doi: 10.1111/j.1399-3011.2005.00282.x (2005).
  7. Suaudeau C, do Rego J-C, Costentin J. Modifications in avoidance reactions of mice, on a second exposure to the hot plate, resist to various amnesia-inducing treatments. Cognitive Brain Research 25, 339-347 doi: 10.1016/j.cogbrainres.2005.06.007 (2005).
  8. Viana A, do Rego J-C, Von Poser GL, Ferraz AF, Heckler AP, Costentin J, Rates SM. The antidepressant-like effect of Hypericum caprifoliatum Cham & Schlecht (Gutiferae) on forced swimming test results from an inhibition of neuronal monoamine uptake. Neuropharmacology 49, 1042-1052 doi: 10.1016/j.neuropharm.2005.06.002 (2005).
  9. do Rego J-C, Chatenet D, Orta MH, Naudin B, Le Cudennec C, Leprince J, Scalbert E, Vaudry H, Costentin J. Behavioral effects of urotensin-II centrally administered in mice. Psychopharmacology 183, 103-117 doi: 10.1007/s00213-005-0140-2 (2005).
  10. Kruszynski R, Fichna J, do Rego J-C, Janecki T., Kosson P., Costentin J., Janecka A. Synthesis and biological activity of N-methylated analogs of endomorphin-2. Bioorg. Med. Chem. 13, 6713-6717 doi: 10.1016/j.bmc.2005.07.051 (2005).
  11. Janecka A, Fichna J, Kruszynski R, Sasaki Y, Ambo A, Costentin J, do Rego J-C. Synthesis and antinociceptive activity of cyclic endomorphin-2 and morphiceptin analogs. Biochem. Pharmacol. 71, 188-195 doi: 10.1016/j.bcp.2005.10.018 (2005).
  12. do Rego J-C, Viana FA, Le Maitre E, Deniel A, Leroux-Nicolet I, Costentin J. Comparisons between anxiety tests for selection of anxious and non anxious mice. Behavioral Brain Research 169, 282-288 doi: 10.1016/j.bbr.2006.01.018 (2006).
  13. Chartrel N, Bruzzone F, Leprince J, Tollemer H, Anouar Y, do Rego J-C, Segalas-Milazzo I, Guilhaudis L, Cosette P, Jouenne T, Simonnet G, Vallarino M, Beauvillain JC, Costentin J, Vaudry H. Structure and functions of the novel hypothalamic RFamide neuropeptides R-RFa and 26RFa in vertebrates. Peptides 27, 1110-1120 doi: 10.1016/j.peptides.2005.06.035 (2006).
  14. do Rego J-C, Leprince J, Chartrel N, Vaudry H, Costentin J. Behavioral effects of 26RFamide and related peptides. Peptides 27, 2715-2721 doi: 10.1016/j.peptides.2006.04.017 (2006).
  15. Viana A, do Rego J-C, Munari L, Dourmap N, Heckler AP, Von Poser GL, Costentin J, Rates MKS. Hypericum caprifoliatum (Guttiferae) Cham. & Schldl. : a species native to south Brazil with antidepressant like activity. Fund. Clin. Pharmacol. 20, 507-514 doi: 10.1111/j.1472-8206.2006.00440.x (2006).
  16. Fichna J, Janecka A, Piestrzeniewicz M, Costentin J, do Rego J-C. Antidepressant-like effect of endomorphin-1 and endomorphin-2 in mice. Neuropsychopharmacology 32, 813-821 doi: 10.1038/sj.npp.1301149 (2007).
  17. Fichna J, do Rego J-C, Chung NN, Lemieux C, Schiller PW, Poels J, Broek JV, Costentin J, Janecka A. Synthesis and characterisation of potent and selective µ-opioid receptor antagonists, [Dmt1,D-2-Nal4]endomorphin-1 (antanal-1) and [Dmt1, D-2-Nal4]endomorphin-2 (antanal-2). J. Med. Chem. 50, 512-520 doi: 10.1021/jm060998u (2007).
  18. Fichna J, Janecka A, Costentin J, do Rego J-C. The endomorphin system and its evolving neurophysiological role. Pharmacol. Rev. 59, 88-123 doi: 10.1124/pr.59.1.3 (2007).
  19. do Rego J-C, Orta M-H, Leprince J, Tonon M-C, Vaudry H, Costentin J. Pharmacological characterization of the receptor mediating anorexigenic action of the octadecaneuropeptide ODN. Evidence for an endozepinergic tone regulating food intake. Neuropsychopharmacology 32, 1641-1648 doi: 10.1038/sj.npp.1301280 (2007).
  20. do Rego J-C, Naïma B, Chosson E, Zahia K, Seguin E, Costentin J. Antidepressant-like effect of hyperfoliatin, a polyisoprenylated phloroglucinol derivative from Hypericum perfoliatum (Clusiaceae) is associated with an inhibition of neuronal monoamines uptake. Eur. J. Pharmacol. 569, 197-203 doi: 10.1016/j.ejphar.2007.05.008 (2007).
  21. Fichna J, do Rego J-C, Janecki T, Staniszewska R, Poels J, Broeck JV, Costentin J, Schiller PW, Janecka A. Novel highly µ-opioid receptor antagonist based on endomorphin-2 structure. Bioorg. Med. Chem. Lett. 18, 1350-1353 doi: 10.1016/j.bmcl.2008.01.009 (2008).
  22. Fichna J, do Rego J-C, Chung NN, Costentin J, Schiller PW, Janecka A. [Dmt1,D-1-Nal3]morphiceptin, a novel opioid peptide analog with high analgesic activity. Peptides 29, 633-638 doi: 10.1016/j.peptides.2007.12.005 (2008).
  23. do Rego J-C, Leprince J, Scalbert E, Vaudry H, Costentin J. Behavioral actions of urotensin II. Peptides 29, 838-844 doi: 10.1016/j.peptides.2007.12.016 (2008).
  24. Viana A, Rates SM, Naudin B, Janin F, Costentin J, do Rego J-C. Effect of acute or three days treatments by two established antidepressants or an extract of Hypericum caprifoliatum Cham & Schltdt (Guttiferae) on basal and stress-induced increase in serum and brain corticosterone levels. J. Psychopharmacology 22, 681-690 doi: 10.1177/0269881107082898 (2008).
  25. Fetissov S, Hamze Sinno M, Coquerel Q, do Rego J-C, Coëffier M, Gilbert D, Hökfelt T, Déchelotte P. Emerging role of autoantibodies appetite-regulating neuropeptides in eating disorders. Nutrition 24, 854-859 doi: 10.1016/j.nut.2008.06.021 (2008).
  26. Sinno MH, Do Rego JC, Coëffier M, Bole-Feysot C, Ducrotté P, Gilbert D, Tron F, Costentin J, Hökfelt T, Déchelotte P, Fetissov SO. Regulation fo feeding and anxiety by alpha-MSH reactive autoantibodies. Psychoneuroendocrinology 34, 140-149 doi: 10.1016/j.psyneuen.2008.08.021 (2008).
  27. Mounien L, do Rego J-C, Bizet P, Boutelet I, Gourcerol G, Fournier A, Brabet P, Costentin J, Vaudry H, Jegou S. Pituitary Adenylate Cyclase-Activating Polypeptide inhibits food intake through activation of the hypothalamic melanocortin system. Neuropsychopharmacology 34, 424-435 doi: 10.1038/npp.2008.73 (2009).
  28. Perlikowska R, Gach K, Fichna J, Toth G, Walkowiak B, Bonnet J-J, do Rego J-C, Janecka A. Biological activity of endomorphin analogs with praline surrogates in position 2. Bioorg. Med. Chem. 17, 3789-3794 doi: 10.1016/j.bmc.2009.04.046 (2009).
  29. Condamine E, Courchay K, do Rego J-C, Leprince J, Mayer C, Davoust D, Costentin J, Vaudry H. Structural and pharmacological characteristics of chimeric peptides derived from peptide E and beta-endorphin reveal the crucial role of the C-terminal YGGFL and YKKGE motifs in their analgesic properties. Peptides 31, 962-972 doi: 1016/j.peptides.2010.01.012 (2010).
  30. Perlikowska R, Fichna J, Wyrebska A, Poels J, Vanden Broeck J, Toth G, Storr M, do Rego J-C, Janecka A. Design, synthesis and pharmacological characterization of endomorphin analogs with non-cyclic amino acid residues in position 2. Basic Clin Pharmacol. Toxicol. 106, 106-113 doi: 10.1111/j.1742-7843.2009.00476.x (2010).
  31. Fichna J, Gach K, Perlikowska R, Cravezic A, Bonnet J-J, do Rego J-C, Janecka A, Storr MA. Novel endomorphin analogues with antagonist activity at the mu-opioid receptor in the gastrointestinal tract. Regul. Pept. 162, 109-114 doi: 10.1016/j.regpep.2010.01.001 (2010).
  32. Perlikowska R, do Rego J-C, Cravezic A, Fichna J, Wyrebska A, Toth G, Janecka A. Synthesis and biological evaluation of cyclic endomorphin-2 analogs. Peptides 31, 339-345 doi: 10.1016/j.peptides.2009.12.002 (2010).
  33. Gach C, do Rego J-C, Fichna J, Storr M, Delbro D, Toth G, Janecka A. Synthesis and biological evaluation of novel peripherally active morphiceptin analogs. Peptides 31, 1617-1624 doi: 10.1016/j.peptides.2010.04.018 (2010).
  34. Vaudry H, do Rego J-C, Le Mevel JC, Chatenet D, Tostivint H, Fournier A, Tonon MC, Pelletier G, Conlon JM, Leprince J. Urotensin II, from fish to human. Ann. NY Acad. Sci. 1200, 53-66 doi: 10.1111/j.1749-6632.2010.05514.x (2010).
  35. Cravezic A, Fichna J, Gach K, Wyrebska A, Perliskowska R, Costentin J, Bonnet JJ, Janecka A, do Rego J-C. Effect of potent endomorphin degradation blockers on analgesic and antidepressant-like responses in mice. Neuropharmacology 61, 1229-1238 doi: 10.1016/j.neuropharm.2011.07.021 (2011).
  36. Fichna J, Perlikowska R, Wyrebska A, Gach K, Piekielna J, do Rego J-C, Toth G, Janecki T, Janecka A. Effect of 2’,6’-dimethyl-L-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs. Bioorg. Med. Chem. 19, 6977-6981 doi: 10.1016/j.bmc.2011.10.040 (2011).
  37. Stein A-C, Viana AF, Müller LG, Nunes JM, Stolz ED, do Rego J-C, Costentin J,  von Poser GL, Rates SMK. Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: A promising new molecular pattern for the development of antidepressant drugs. Behav. Brain Res. 228, 66-73 doi: 10.1016/j.bbr.2011.11.031 (2012).
  38. Garcia FD, Coquerel Q, do Rego J-C, Cravezic A, Bole-Feysot C, Kiive E, Déchelotte P, Harro J, Fetissov SO. Anti-neuropeptide Y plasma immunoglobulins in relation to mood and appetite in depressive disorder. Psychoneuroendocrinology 37, 1457-1467 doi: 10.1016/j.psyneuen.2012.01.015 (2012).
  39. Stolz ED, Viana AF, Hasse DR, von Poser GL, do Rego J-C, Rates SMK. Uliginosin B presents antinociceptive effect mediated by dopaminergic and opioid systems in mice. Prog. Neuropsychopharmacol. Biol. Psychiatry 39, 80-87 doi: 10.1016/j.pnpbp.2012.05.012 (2012).
  40. Neveu C, Lefranc B, Tasseau O, do Rego J-C, Bourmaud A, Chan P, Bauchat P, Le Marec O, Chuquet J, Guilhaudis L, Boutin JA, Ségalas-Milazzo I, Costentin J, Vaudry H, Baudy-Floc'h M, Vaudry D, Leprince J. Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist. J. Med. Chem. 55, 7516-7524 doi: 10.1021/jm300507d (2012).
  41. Braga A, Stein AC, Dischkaln Stolz E, Dallegrave E, Buffon A, do Rego J-C, Gosmann G, Fialho Viana A, Kuze Rates SM. Repeated administration of an aqueous spray-dried extract of the leaves of Passiflora alata Curtis (Passifloraceae) inhibits body weight gain without altering mice behavior. J. Ethnopharmacol. 145, 59-66 doi: 10.1016/j.jep.2012.10.034 (2013).
  42. Mayeur A, Duclos C, Honoré A, Gauberti M, Drouot L, do Rego J-C, Bon-Mardion N,Jean L, Vérin E, Emery E, Lemarchant S, Vivien D, Boyer O, Marie JP, Guérout N. Potential of olfactory unsheathing cells from different sources for spinal cord repair. PLoS One. 8, 1-12 doi: 10.1371/journal.pone.0062860 (2013).
  43. Takagi K, Legrand R, Asakawa A, Amitani H, François M, Tennoune N, Coëffier M,Claeyssens S, do Rego J-C, Déchelotte P, Inui A, Fetissov SO. Anti-ghrelin immunoglobulins modulate ghrelin stability and its orexigenic effect in obese mice and humans. Nat. Commun. 4 :2685, 1-11 doi: 10.1038/ncomms3685 (2013).
  44. Perlikowska R, Piekielna J, Fichna J, do Rego J-C, Toth G, Janecki T, Janecka A. Pharmacological Properties of Novel Cyclic Pentapeptides with µ-opioid Receptor Agonist Activity. Med Chem. 10, 154-61 doi: 10.2174/157340641002140131161135 (2014).
  45. Jésus P, Ouelaa W, François M, Riachy L, Guérin C, Aziz M, do Rego J-C,Déchelotte P, Fetissov SO, Coëffier M. Alteration of intestinal barrier function during activity-based anorexia in mice. Clin. Nutr. 33, 1046-1053 doi: 10.1016/j.clnu.2013.11.006 (2014).
  46. Lemarchant S, Pruvost M, Hébert M, Gauberti M, Hommet Y, Briens A, Maubert E, Gueye Y, Féron F, Petite D, Mersel M, do Rego JC, Vaudry H, Koistinaho J, Ali C, Agin V, Emery E, Vivien D. tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury. Neurobiol. Dis. 66, 28-42 doi: 10.1016/j.nbd.2014.02.005 (2014).
  47. Coquerel D, Neviere R, Delile E, Mulder P, Marechal X, Montaigne D, Renet S, Remy-Jouet I, Gomez E, Henry JP, do Rego JC, Richard V, Tamion F. Gene deletion of protein tyrosine phosphatase 1B protects against sepsis-induced cardiovascular dysfunction and mortality. Arterioscler Thromb. Vasc. Biol. 34, 1032-44 doi: 10.1161/ATVBAHA.114.303450 (2014).
  48. Perlikowska R, Malfacini D, Cerlesi MC, Calo' G, Piekielna J, Floriot L, Henry T, do-Rego JC, Tömböly C, Kluczyk A, Janecka A. Pharmacological characterization of endomorphin-2-based cyclic pentapeptides with methylated phenylalanine residues. Peptides 55, 145-50 doi: 10.1016/j.peptides.2014.03.001 (2014).
  49. Sałaga M, Polepally PR, Sobczak M, Grzywacz D, Kamysz W, Sibaev A, Storr M, Do Rego JC, Zjawiony JK, Fichna J. Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome. J. Pharmacol. Exp. Ther. 350, 69-78 doi: 10.1124/jpet.114.214239 (2014).
  50. Aligny C, Roux C, Dourmap N, Ramdani Y, Do-Rego JC, Jégou S, Leroux P, Leroux-Nicollet I, Marret S, Gonzalez BJ. Ketamine alters cortical integration of GABAergic interneurons and induces long-term sex-dependent impairments in transgenic Gad67-GFP mice. Cell. Death. Dis. 5, e1311. doi: 10.1038/cddis.2014.275 (2014).
  51. Perlikowska R, Piekielna J, Mazur M, Koralewski R, Olczak J, do Rego JC, Fichna J, Modranka J, Janecki T, Janecka A. Antinociceptive and antidepressant-like action of endomorphin-2 analogs with proline surrogates in position 2. Bioorg. Med. Chem. 22, 4803-4809 doi: 10.1016/j.bmc.2014.06.056 (2014).
  52. Tennoune N, Chan P, Breton J, Legrand R, Chabane YN, Akkermann K, Järv A, Ouelaa W, Takagi K, Ghouzali I, Francois M, Lucas N, Bole-Feysot C, Pestel-Caron M, do Rego JC, Vaudry D, Harro J, Dé E, Déchelotte P, Fetissov SO. Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide α-MSH, at the origin of eating disorders. Transl. Psychiatry 4:e458. doi: 10.1038/tp.2014.98 doi: 10.1038/tp.2014.98 (2014).
  53. Gach K, Belkacemi O, Lefranc B, Perlikowski P, Masson J, Walet-Balieu ML, Do-Rego JC, Galas L, Schapman D, Lamtahri R, Tonon MC, Vaudry D, Chuquet J, Leprince J. Detection, characterization and biological activities of [bisphospho-thr3,9]ODN, an endogenous molecular form of ODN released by astrocytes. Neuroscience 290, 472-84 doi: 10.1016/j.neuroscience.2015.01.045 (2015).
  54. Tennoune N, Legrand R, Ouelaa W, Breton J, Lucas N, Bole-Feysot C, do Rego JC, Déchelotte P, Fetissov SO. Sex-related effects of nutritional supplementation of Escherichia coli: relevance to eating disorders. Nutrition 31, 498-507 doi: 10.1016/j.nut.2014.11.003 (2015).
  55. François M, Barde S, Achamrah N, Breton J, do Rego JC, Coëffier M, Hökfelt T, Déchelotte P, Fetissov SO. The number of preproghrelin mRNA expressing cells is increased in mice with activity-based anorexia. Neuropeptides 51, 17-23 doi: 10.1016/j.npep.2015.04.003 (2015).
  56. Piekielna J, Perlikowska R, do-Rego JC, do-Rego JL, Cerlesi MC, Calo G, Kluczyk A, Łapiński K, Tömböly C, Janecka A. Synthesis of mixed opioid affinity cyclic endomorphin-2 analogues with fluorinated phenylalanines. ACS Med. Chem. Lett. 6, 579-83 doi: 10.1021/acsmedchemlett.5b00056 (2015).
  57. Lecointre M, Vézier C, Bénard M, Ramdani Y, Dupré N, Brasse-Lagnel C, Henry VJ, Roy V, Marret S, Gonzalez BJ, Jégou S, Leroux-Nicollet I. Age-dependent alterations of the NMDA receptor developmental profile and adult behavior in postnatally ketamine-treated mice. Dev. Neurobiol. 75, 315-33 doi: 10.1002/dneu.22232 (2015).
  58. Lacaille H, Duterte-Boucher D, Liot D, Vaudry H, Naassila M, Vaudry D. Comparison of the deleterious effects of binge drinking-like alcohol exposure in adolescent and adult mice. J. Neurochem. 132, 629-41 doi: 10.1111/jnc.13020 (2015).
  59. Pelloux Y, Costentin J, Duterte-Boucher D. Differential involvement of anxiety and novelty preference levels on oral ethanol consumption in rats. Psychopharmacology 23, 2711-2721 doi: 10.1007/s00213-015-3910-5 (2015).
  60. Salaga M, Polepally PR, Zielinska M, Marynowski M, Fabisiak A, Murawska N, Sobczak K, Sacharczuk M, Do Rego JC, Roth BL, Zjawiony JK, Fichna J. Salvinorin A analogs PR-37 and PR-38 attenuate compound 48/80-induced itch responses in mice. Br. J. Pharmacol. 172, 4331-4341 doi: 10.1111/bph.13212 (2015).
  61. Breton J, Tennoune N, Lucas N, Francois M, Legrand R, Jacquemot J, Goichon A, Guérin C, Peltier J, Pestel-Caron M, Chan P, Vaudry D, do Rego JC, Liénard F, Pénicaud L, Fioramonti X, Ebenezer IS, Hökfelt T, Déchelotte P, Fetissov SO. Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth. Cell Metab. 9, 324-334 doi: 10.1016/j.cmet.2015.10.017 (2016).
  62. Achamrah N, Nobis S, Breton J, Jésus P, Belmonte L, Maurer B, Legrand R, Bôle-Feysot C, do Rego JL, Goichon A, Rego JC, Déchelotte P, Fetissov SO, Claeyssens S, Coëffier M. Maintaining physical activity during refeeding improves body composition, intestinal hyperpermeability and behavior in anorectic mice. Sci Rep. 6:21887. doi: 10.1038/srep21887 (2016).
  63. Legrand R, Lucas N, Breton J, Azhar S, do Rego JC, Déchelotte P, Coëffier M, Fetissov SO. Ghrelin treatment prevents development of activity based anorexia in mice. Eur Neuropsychopharmacol 26, 948-958 doi: 10.1016/j.euroneuro.2016.03.010 (2016).
  64. François M, Takagi K, Legrand R, Lucas N, Beutheu S, Bôle-Feysot C, Cravezic A, Tennoune N, do Rego JC, Coëffier M, Inui A, Déchelotte P, Fetissov SO. Increased Ghrelin but Low Ghrelin-Reactive Immunoglobulins in a Rat Model of Methotrexate Chemotherapy-Induced Anorexia. Front Nutr. 3:23. doi: 10.3389/fnut.2016.00023 (2016).
  65. Achamrah N, Nobis S, Goichon A, Breton J, Legrand R, do Rego JL, do Rego JC, Déchelotte P, Fetissov SO, Belmonte L, Coëffier M. Sex differences in response to activity-based anorexia model in C57Bl/6 mice. Physiol Behav. 170:1-5. doi: 10.1016/j.physbeh.2016.12.014 (2017).
  66. Briet C, Bourdenet G, Rogner UC, Becourt C, Tardivel I, Drouot L, Arnoult C, do Rego JC, Prevot N, Massaad C, Boyer O, Boitard C. The Spontaneous Autoimmune Neuromyopathy in ICOSL-/- NOD Mice Is CD4+ T-Cell and Interferon-γ Dependent. Front Immunol. 8:287. doi: 10.3389/fimmu.2017.00287 (2017).
  67. Nobis S, Morin A, Achamrah N, Belmonte L, Legrand R, Chan P, do Rego JL, Vaudry D, Gourcerol G, Déchelotte P, Goichon A, Coëffier M. Delayed gastric emptying and altered antrum protein metabolism during activity-based anorexia. Neurogastroenterol Motil. 30(7):e13305. doi: 10.1111/nmo.13305 (2018).
  68. Nobis S, Goichon A, Achamrah N, Guérin C, Azhar S, Chan P, Morin A, Bôle-Feysot C, do Rego JC, Vaudry D, Déchelotte P, Belmonte L, Coëffier M. Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia. Sci Rep. 8(1):7233. doi: 10.1038/s41598-018-25548-9 (2018).
  69. Nobis S, Achamrah N, Goichon A, L'Huillier C, Morin A, Guérin C, Chan P, do Rego JL, do Rego JC, Vaudry D, Déchelotte P, Belmonte L, Coëffier M. Colonic Mucosal Proteome Signature Reveals Reduced Energy Metabolism and Protein Synthesis but Activated Autophagy during Anorexia-Induced Malnutrition in Mice. Proteomics. 18(15):e1700395. doi: 10.1002/pmic.201700395 (2018).
  70. Værøy H, Adori C, Legrand R, Lucas N, Breton J, Cottard C, do Rego JC, Duparc C, Louiset E, Lefebvre H, Déchelotte P, Western E, Andersson S, Hökfelt T, Fetissov SO. Autoantibodies reactive to adrenocorticotropic hormone can alter cortisol secretion in both aggressive and nonaggressive humans. Proc Natl Acad Sci U S A. 115, E6576-E6584 doi: 10.1073/pnas.1720008115 (2018).
  71. Chollat C, Lecointre M, Leuillier M, Remy-Jouet I, Do Rego JC, Abily-Donval L, Ramdani Y, Richard V, Compagnon P, Dureuil B, Marret S, Gonzalez BJ, Jégou S, Tourrel F. Beneficial Effects of Remifentanil Against Excitotoxic Brain Damage in Newborn Mice. Front Neurol. 10:407. doi: 10.3389/fneur.2019.00407 (2019).
  72. Salameh E, Meleine M, Gourcerol G, do Rego JC, do Rego JL, Legrand R, Breton J, Aziz M, Guérin C, Coëffier M, Savoye G, Marion-Letellier R. Chronic colitis-induced visceral pain is associated with increased anxiety during quiescent phase. Am J Physiol Gastrointest Liver Physiol. 316, G692-G700 doi: 10.1152/ajpgi.00248.2018 (2019).
  73. L'Huillier C, Jarbeau M, Achamrah N, Belmonte L, Amamou A, Nobis S, Goichon A, Salameh E, Bahlouli W, do Rego JL, Déchelotte P, Coëffier M. Glutamine, but not Branched-Chain Amino Acids, Restores Intestinal Barrier Function during Activity-Based Anorexia. Nutrients. 11(6). pii: E1348. doi: 10.3390/nu11061348 (2019).
  74. Betti AH, Antonio CB, Herzfeldt V, Pitta MGDR, da Rocha Pitta I, do Rego JL, do Rego JC, Vaudry D, Rates SMK. PT-31, a putative α2-adrenoceptor agonist, is effective in schizophrenia cognitive symptoms in mice. Behav Pharmacol. (7):574-587. doi: 10.1097/FBP.0000000000000494 (2019).
  75. Breton J, Legrand R, Achamrah N, Chan P, do Rego JL, do Rego JC, Coëffier M, Déchelotte P, Fetissov SO. Proteome modifications of gut microbiota in mice with activity-based anorexia and starvation: Role in ATP production. Nutrition. 67-68 :110557. doi: 10.1016/j.nut.2019.110557 (2019).
  76. Dominique M, Legrand R, Galmiche M, Azhar S, Deroissart C, Guérin C, do Rego JL, Léon F, Nobis S, Lambert G, Lucas N, Déchelotte P. Changes in Microbiota and Bacterial Protein Caseinolytic Peptidase B During Food Restriction in Mice: Relevance for the Onset and Perpetuation of Anorexia Nervosa. Nutrients. 18;11(10). pii: E2514. doi: 10.3390/nu11102514 (2019).
  77. Breton J, Giallourou N, Nobis S, Morin A, Achamrah N, Goichon A, Belmonte L, Dechelotte P, do Rego JL, Coëffier M, Swann J. Characterizing the metabolic perturbations induced by activity-based anorexia in the C57Bl/6 mouse using 1H NMR spectroscopy. Clin Nutr. pii: S0261-5614(19)33118-8. doi: 10.1016/j.clnu.2019.10.026 (2019).
  78. Lucas N, Legrand R, Deroissart C, Dominique M, Azhar S, Le Solliec MA, Léon F, do Rego JC, Déchelotte P, Fetissov SO, Lambert G. Hafnia alvei HA4597 Strain Reduces Food Intake and Body Weight Gain and Improves Body Composition, Glucose, and Lipid Metabolism in a Mouse Model of Hyperphagic Obesity. Microorganisms. 8(1). pii: E35. doi: 10.3390/microorganisms8010035 (2019).
  79. Lucas N, Azhar S, Procida A, Deroissart C, Dominique M, Nobis S, Guérin C, Léon F, do Rego JC, Breton J, Coëffier M, Legrand R. Intestinal lymphatics alteration in mouse models of energy imbalance. Nutrition. doi: 10.1016/j.nut.2019.110714 (2019).
  80. Legrand R, Lucas N, Dominique M, Azhar S, Deroissart C, Le Solliec MA, Rondeaux J, Nobis S, Guérin C, Léon F, do Rego JC, Pons N, Le Chatelier E, Ehrlich SD, Lambert G, Déchelotte P, Fetissov SO. Commensal Hafnia alvei strain reduces food intake and fat mass in obese mice-a new potential probiotic for appetite and body weight management. Int J Obes (Lond). doi: 1038/s41366-019-0515-9 (2020).
  81. El Mehdi M, Takhlidjt S, Khiar F, Prévost G, do Rego JL, do Rego JC, Bénani A, Nedelec E, Godefroy D, Arabo A, Lefranc B, Leprince J, Anouar Y, Chartrel N, Picot M. Glucose homeostasis is impaired in mice deficient for the neuropeptide 26RFa (QRFP). BMJ Open Diabetes Res Care. doi: 10.1136/bmjdrc-2019-000942 (2020).
  82. Arias HR, Do Rego JL, Do Rego JC, Chen Z, Anouar Y, Scholze P, Gonzales EB, Huang R, Chagraoui A. Coronaridine congeners potentiate GABAA receptors and induce sedative activity in mice in a benzodiazepine-insensitive manner. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Jul 13;101:109930. doi: 10.1016/j.pnpbp.2020.109930 Epub 2020 Mar 16. PMID: 32194202.
  83. Breton J, Tirelle P, Hasanat S, Pernot A, L'Huillier C, do Rego JC, Déchelotte P, Coëffier M, Bindels LB, Ribet D. Gut microbiota alteration in a mouse model of Anorexia Nervosa. Clin Nutr. 2021 Jan;40(1):181-189. doi: 10.1016/j.clnu.2020.05.002. Epub 2020 May 11. PMID: 32460959.
  84. L'Huillier C, Jarbeau M, Pingeon F, Bahlouli W, Salameh E, Amamou A, Goichon A, Tirelle P, do Rego JL, Déchelotte P, Coëffier M. Influence of Glutamine and Branched-Chain Amino Acids Supplementation during Refeeding in Activity-Based Anorectic Mice. Nutrients. 2020 Nov 14;12(11):3510. doi: 10.3390/nu12113510. PMID: 33202638; PMCID: PMC7696484.
  85. Pieronne-Deperrois M, Guéret A, Djerada Z, et al. Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice. ESC Heart Fail. 2021;8(3):1933-1943. doi: 10.1002/ehf2.13219
  86. Tirelle P, Breton J, Kauffmann A, et al. Gut microbiota depletion affects nutritional and behavioral responses to activity-based anorexia model in a sex-dependent manner. Clin Nutr. 2021;40(5):2734-2744. doi:10.1016/j.clnu.2021.04.014
  87. Dominique M, Lucas N, Legrand R, et al. Effects of Bacterial CLPB Protein Fragments on Food Intake and PYY Secretion. Nutrients. 2021;13(7):2223. Published 2021 Jun 29. doi:10.3390/nu13072223
  88. Le Solliec MA, Arabo A, Takhlidjt S, et al. Acute but Not Chronic Central Administration of the Neuropeptide 26RFa (QRFP) Improves Glucose Homeostasis in Obese/Diabetic Mice. Neuroendocrinology. 2022;112(11):1104-1115. doi:10.1159/000522287
  89. Tirelle P, Salaün C, Kauffmann A, et al. Intestinal Epithelial Toll-like Receptor 4 Deficiency Modifies the Response to the Activity-Based Anorexia Model in a Sex-Dependent Manner: A Preliminary Study. Nutrients. 2022;14(17):3607. Published 2022 Aug 31. doi:10.3390/nu14173607
  90. Leuillier M, Duflot T, Ménoret S, et al. CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury. J Adv Res. 2023;43:163-174. doi:10.1016/j.jare.2022.03.004
  91. Atmani K, Wuestenberghs F, Baron M, et al. Bladder-colon chronic cross-sensitization involves neuro-glial pathways in male mice. World J Gastroenterol. 2022;28(48):6935-6949. doi:10.3748/wjg.v28.i48.6935
  92. Nicol M, Lahaye E, El Mehdi M, do Rego JL, do Rego JC, Fetissov SO. Lactobacillus salivarius and Lactobacillus gasseri supplementation reduces stress-induced sugar craving in mice. Eur Eat Disord Rev. 2024;32(6):1041-1054. doi:10.1002/erv.3004
  93. Værøy H, Lahaye E, Dubessy C, et al. Immunoglobulin G is a natural oxytocin carrier which modulates oxytocin receptor signaling: relevance to aggressive behavior in humans. Discov Ment Health. 2023;3(1):21. Published 2023 Oct 19. doi:10.1007/s44192-023-00048-z
  94. Perlikowska R, Silva J, Alves C, et al. Neuroprotective and Anti-inflammatory Effects of Rubiscolin-6 Analogs with Proline Surrogates in Position 2. Neurochem Res. 2024;49(4):895-918. doi: 10.1007/s11064-023-04070-z
  95. Salaün C, Courvalet M, Rousseau L, et al. Sex-dependent circadian alterations of both central and peripheral clock genes expression and gut-microbiota composition during activity-based anorexia in mice. Biol Sex Differ. 2024;15(1):6. Published 2024 Jan 12. doi:10.1186/s13293-023-00576-x
  96. Demangeat T, Loison L, Huré M, et al. Gut Microbiota Regulates Food Intake in a Rodent Model of Intermittent Limited Access to Palatable Food. Int J Eat Disord. Published online December 2, 2024. doi:10.1002/eat.24339